Real-time fluorescence imaging with the ENDOCAM Logic 4K platform
System green from Richard Wolf is an excellent visualization of visceral perfusion solution for real-time ICG/NIR fluorescence imaging which meets the highest standards of endoscopic imaging. Indocyanine Green (ICG, available as Verdye in many territories*) is a tricarbocyanine dye, when used with NIR camera systems, will fluoresce and allow visualization of anatomical structures.
ICG/NIR fluorescence imaging has become one of the most valuable technologies in the field of minimally invasive surgery for applications including intraoperative assessment of visceral perfusion (e.g., enteroanastomosis), visualization of biliary structures in fluorescence cholangiography, or lymph node mapping in oncological procedures (e.g. visualization of the sentinel lymph nodes in case of lymphadenectomy).
* Diagnostic Green is the leading provider of high quality fluorescence products worldwide including ICG. For full prescribing information relating to Verdye, please consult https://diagnosticgreen.com/row/product-information/ .
System green enables standard white light endoscopy with high-resolution image quality at any time. The system can therefore be used without limitations even in white light mode.
In the greenICG mode, the conventional white light endoscopic image is simultaneously combined with the ICG/NIR image information in real time, at the touch of a button. This allows the tissue to be differentiated with a high level of detail and contrast, thus allowing the surgeon to easily differentiate anatomy during the surgical procedure.
The greenICG pure mode enables specific, high-contrast visualization as well as differentiation of tissue structures, e.g., in the case of lymph nodes and the lymphatic channels. The grayscale visualization enables detailed examination of the key structures.
Upon administration, ICG enters the blood stream and immediately binds to the plasma proteins and circulates throughout the entire vascular system. The absorption spectrum of ICG (indocyanine green, Verdye, Diagnostic Green) is located in the near-infrared range (NIR). ICG absorbs the light in the range of 600 nm to 900 nm and emits the fluorescence between 800 nm up to 850 nm. In order to visualise the ICG fluorescence, a ICG / NIR camera system, such as System green is utilised. Thus, it is possible to detect the fluorescence intraoperatively and to visualize fluorescence with System green. The use of NIR light enables the surgeon to see structures more clearly.
ENDOCAM Logic 4K enables endoscopic imaging in native 4K/UHD resolution with the simultaneous provision of additional ICG/NIR image information in two different Special Imaging Modes.
- Richard Wolf Special Imaging Modes:
greenICG (white light image with ICG overlay)
greenICG pure (grayscale image with ICG overlay)
- High-resolution endoscopic image with crystal-clear 4K/UHD quality
- ICG-ready: Existing devices can simply be upgraded by means of a software update
- Powerful, laser-free LED light source for perfect illumination in ICG/NIR and white light endoscopy
Detailed fluorescence imaging irrespective of the ICG concentration thanks to automatic regulation of the NIR and white light intensity
Latest LED technology reduces service and operating costs thanks to its long service life (up to 15,000 hours)
Virtually silent for a pleasant working environment
Compatible with the core nova operating theatre integration system
- For ENDOCAM Logic platform
Also suitable for use in white light endoscopy with no limitations
Digital image processing and signal transmission with dedicated powerful NIR sensor for high fluorescence sensitivity
Extremely lightweight and ergonomic for excellent handling
Integrated lens (f = 24 mm) tailored to use in laparoscopy
The new fiber design and specifically the bright lens system ensures crystal-clear images and a longer service life.
4K/UHD endoscope for a bright, crystal-clear, razor-sharp image
Optimized for ICG/NIR applications
Also ideal for standard white light endoscopy
Natural color visualization in white light mode as well as in System green mode greenICG
Fusion fiber light cables meet the highest standards in endoscopy.
Extremely high temperature resistance
Much longer service life
Easier to handle thanks to improved flexibility and steel kink protection
Recommended for 4K systems due to improved efficiency
High light transmission for uniform illumination
Indocyanine Green (ICG, known as Verdye, Diagnostic Green)
Indocyanine green (ICG) is a tricarbocyanine dye with both hydrophilic and lipophilic properties. Before administration, the powder must be reconstituted with water for injection. Verdye is intended for intravenous injection (i.v.) via an injection needle, a central or peripheral catheter or cardiac catheter. Following I.V. administration, ICG is rapidly bound to plasma proteins, of which beta-apolipoprotein B is the principle carrier (95%) and remains in the blood vessels.
ICG is cleared exclusively through the liver, and then eliminated through the bile. It does not undergo metabolism.
- Well tolerated*
- Excellent safety profile
- Cleared exclusively through the liver
- Half-life of 3-4 minutes
- Rapidly bound to plasma protein
- Undergoes no significant extrahepatic or enterohepatic circulation
*Undesirable effects: It is known that injection of Indocyanine Green preparations can in very rare cases cause nausea and anaphylactic reactions (<1/10,000).
For full prescribing information relating to Verdye, please consult https://diagnosticgreen.com/row/product-information/.
Discover the 3D model of System green with the Augmented Reality app.
Here is how it works:
- Download the "RIWO AR" app to your smartphone or tablet.
- Start the app on your device.
- Scan the image on the right with the app.
Have fun discovering the Augmented Reality world of Richard Wolf!