Redefine biodegradation!

BioactIF OSTEOTRANS is the name for the new generation of bioactive and bioresorbable interference screws from Richard Wolf. The unique Osteotrans composite material made of Poly-L-Lactide (PLLA) and unsintered Hydroxylapatite (uHA) demonstrates an osteoconductive effect in bones. Trabecular structures grow into the surface of the implant from the surrounding bone within a short time frame.

The distribution of uHA particles generated uniformly by a special manufacturing process also creates a permanent buffer of the lactic acid produced in the course of degradation of the PLLA components and hence prevents inflammatory reactions in bones and tissue, as well as encapsulation of the implant.

The mechanical characteristics generated in the course of the special manufacturing method for the material are comparable with the properties of the surrounding bone. The transfer of forces from the surrounding bone to the implant is thereby ensured. This is a key prerequisite for activating the osteoblasts. Complete bone reconstruction can hence be achieved for this area. The implant can easily be seen in X-ray visualization.

Our screw series at a glance

In the application

  • Extensive range
  • Direct connection with the bone, osteoconductive effective
  • Optimum physiological properties thanks to composite material made of Poly-L-Lactide (PLLA) and unsintered Hydroxylapatite (uHA)
  • Acid buffering to prevent rejection reactions
  • No osteolysis
  • Long-term bioresorption
  • Bone formation through remodeling process

Bioactive and bioresorbable interference screws


Osteoconductivity & osteobinding

  • Bone grows into the surface of the implant
  1. Physiological environment by buffering the acid pH value of the accumulated lactic acid by uHA particles
  2. No encapsulation

Biodegradation & bioresorption

Hydrolysis (PLLA) & osteoclasts (HA)

  • Homogenous degradation of PLLA particles thanks to semi-crystalline structure
  • Osteoclastic degradation of uHA particles

Bone regeneration

  • Implant has similar mechanical properties to the surrounding bone
  1. Force transfer
  2. Load
  3. Bone growth

Subject to modifications. Please note that some products may not be available in all countries. Please always take note of the information that is provided with the product. For more detailed information, please consult with your contact partner or directly with Richard Wolf GmbH.

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